Arkansas Children's Hospital Research Institute (ACHRI)
Currently Enrolling Clinical Trials
If you do not find a study that interests you, please consider enrolling in our Research Volunteer Program. You can select the types of studies in which you are interested, and our staff will contact you when a study becomes available in one of those areas.
Metabolic Biomarkers of Autism: Predictive Potential and Genetic Susceptibility
Study Description:
An NIH-sponsored autism research study at Arkansas Children’s Hospital Research Institute is recruiting children 3-10 years of age with the diagnosis of autistic disorder, their siblings, and also control/unaffected children. The study is directed by Dr. S. Jill James, Professor in the Department of Pediatrics, who will analyze blood samples from these children as well as their parents and their siblings to better understand the metabolic pathology that may contribute to the symptoms and development of autism.
The research study is also recruiting children with normal and abnormal social development who are 18-36 months of age to test whether specific metabolic biomarkers are predictive of a diagnosis of autism.
For more information about this study, please call the study coordinator, Lisa Seidel, at 501-364-4669 or toll-free at 1-800-283-7428.
A Randomized, Multicenter, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of a Combination Product Containing Sumatriptan and Naproxen Sodium for the Acute Treatment of Migraine in Adolescents
Study Description:
This study will evaluate the effectiveness of a range of doses of a combination product containing sumatriptan and naproxen sodium for the acute treatment of migraines in adolescents age 12-17 years old.
The study will last up to 25 weeks and includes up to 3 visits during the 25 weeks for eligible subjects.
For more information, contact Robin Gibson, RN at 501-364-1542.
Beginnings study: Effects of Diet on Metabolism, Body Composition, and Brain function in infants/children
Study Description:
Have you ever wondered...
-Is Breast(feeding) really best?
-Are chubby babies destined to be overweight adults?
-If soy foods are healthy for me, is soy formula good for babies?
We have! These are just a few of the many questions being answered by the scientists at the Arkansas Children's Nutrition Center (ACNC) through the Beginnings study. The ACNC is one of only six Human Nutrition Research Centers funded by the U.S. Department of Agriculture. The ACNC is located on the campus of the Arkansas Children's Hospital and the scientists are faculty at the University of Arkansas for Medical Sciences (UAMS).
Beginnings is a long-term research study of infants/children from birth through school age. Moms can enroll their healthy babies between 4-8 weeks old, once they have decided on the right feeding type for their baby - breast milk, milk-based formula, or soy-based formula. We are still enrolling infants in all feeding groups, but we are the most interested in finding infants fed soy-based formula. Moms and babies come to the ACNC for up to eight study visits during the first year of life, at 1-, 2-, 3-, 4-, 5-, 6-, 9-, and 12 months of age, then annually of the rest of the study. At each visit, we measure the growth, brain function, development and diet of the infant/child. At some visits, we also assess body composition (percent body fat), general development and behavior, and the size of some organs with an ultrasound.
The Beginnings study has been approved by the UAMS Institutional Review Board (IRB), which is an independent committee of scientists, doctors, and community leaders not involved in this research project. The IRB is an ethics board that reviews all research projects to make sure they are safe. Although we cannot pay people to be a part of a research study, we offer benefits such as formula, diapers, travel stipend, gift cards, or other incentives.
For more information about the Beginnings study, please call our Recruiter, Andrea Stokes, at (501) 364-3309 or toll-free at (866)423-1311 (toll free) or ACNCStudies@uams.edu. You can also visit us on-line at:www.uams.edu/acnc
Study Description:
The Brain Power study is a short-term nutrition research study designed to help scientists determine how the diet of children as infants affects their current brain function. Participants in the study are healthy adolescents, ages 7 ½ through 8 ½ who were fed a mostly soy-based formula diet from birth through 12 months. Participants attend between 1 and 3 study visits on the ACH campus. Components of the study include thorough body measurements of the child; psychological testing; brain function testing; and an fMRI scan by ACH’s Department of Radiology. Compensation may be provided in the form of cash, check or a cash card beginning with $25.00 for the first visit and $50.00 each for both the second and third visits. Additionally, a bonus of $175.00 will be given for completing all three visits. Partially completed visits may be partially compensated.
For more information about the Brain Power study, please contact the ACNC Recruitment Center at (501)364-3309, toll-free at (866)423-1311, or via e-mail at acncstudies@uams.edu. You can also visit us online at www.uams.edu/acnc.
An open-label study to evaluate the single-dose pharmacokinetics and safety of ceftobiprole in pediatric subjects 3 months to < 18 years of age undergoing treatment with systemic antibiotics
Study Description:
The study will measure the amount of study drug (ceftobiprole) in the blood of children after receiving one dose. The study will also see how well children tolerate one dose of the study drug (ceftobiprole).
